Cancer drugmaker stocks present an interesting opportunity to investors. Although there is no guarantee a company with a drug in the pipeline will be approved let alone popular, (two reasons why the biotech industry is wrought with risk) getting in early can mean big returns if the company releases a blockbuster drug. (STAY AHEAD OF THE CURVE: Follow Kapitall on Twitter)
These stocks can quickly rise in value if they pass certain goals in testing, reach approval, or reach commercial success. They can also rise in value when the companies present their research at the American Society of Clinical Oncology (ASCO), which holds their annual meeting in June. These presentations can be real game changers for the world of medicine, and for stock values.
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The society will be posting research abstracts for the meeting on its website May 16th. Until then, there are seven companies with stocks expected to present at this year's ASCO meeting.
TheStreet has compiled some need-to-know information on these companies for investors. Do you agree it would be wise to keep these names on your radar?
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1. Celldex Therapeutics (CLDX, Earnings, Analysts, Financials): Not much is known, but the company will discuss Phase IIb study of CDX-011 in refractory breast cancer. According to TheStreet, "Celldex enrolled 120 patients with advanced breast cancer that over-expresses a protein known as GPNMB (confirmed by an independent test). The patients, all of whom no longer respond to currently approved treatments, are then randomized to receive either CDX-011 or physician's choice of treatment. The primary endpoint of the study is overall response rate."
2. Arqule (ARQL, Earnings, Analysts, Financials): The company will present on A phase II study of tivantinib (ARQ-197) in second-line liver cancer. "Top-line data from this phase II study were released in January. Liver cancer patients who progressed after first-line therapy were randomized 2:1 to receive tivantinib or a placebo. The study met its primary endpoint with tivantinib demonstrating a 56% improvement in time to tumor regrowth compared to the placebo."
3. Johnson & Johnson (JNJ, Earnings, Analysts, Financials): At ASCO, JNJ will present Phase III study of Zytiga in "pre-chemo" prostate cancer patients. "At this point, the Zytiga study is the biggest attention grabber at ASCO from a Wall Street perspective because the results have far-reaching impact not only on J&J but prostate cancer drug competitors Medivation (MDVN) and Dendreon (DNDN).
4. Ariad Pharmaceuticals (ARIA, Earnings, Analysts, Financials): Will present on six-month, follow-up data from the pivotal phase III study of ponatinib in chronic myelogenous leukemia. "Results from the first three months of the ponatinib PACE study were presented last December… Investors will be looking for six-month response rates to be higher than what was seen last December."
5. Aveo Pharmaceuticals (AVEO, Earnings, Analysts, Financials): According to TheStreet, Aveo will give a full presentation of results from the phase III study of tivozanib in kidney cancer. "Top-line results from the kidney cancer study were announced in early January with tivozanib demonstrating a progression-free survival of 11.9 months compared to 9.1 months for Nexavar."
6. Array BioPharma (ARRY, Earnings, Analysts, Financials): Presenting on Selumetinib in second-line non-small cell lung cancer. Last September's "survival trend favoring selumetinib wasn't statistically significant but full details on the drug's efficacy, including PFS and response rate endpoints, will be presented at ASCO."
7. Oncothyreon (ONTY, Earnings, Analysts, Financials): Phase II studies of PX-866 in solid tumors. "Phase I trials showed PX-866 to be well tolerated with some evidence of anti-cancer activity. Oncothyreon is conducting phase II studies of PX-866 in combination with other drugs in non-small cell lung cancer, glioblastoma, prostate cancer, colon cancer and head-and-neck cancer."
(Rebecca Lipman does not own shares in any of the companies mentioned above. Data sourced from TheStreet.)
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Dig Deeper: Access Company Snapshots, Charts, Filings
- Celldex Therapeutics (CLDX, Chart, Download SEC Filings)
- Arqule (ARQL, Chart, Download SEC Filings)
- Johnson & Johnson (JNJ, Chart, Download SEC Filings)
- Ariad Pharmaceuticals (ARIA, Chart, Download SEC Filings)
- Aveo Pharmaceuticals (AVEO, Chart, Download SEC Filings)
- Array BioPharma (ARRY, Chart, Download SEC Filings)
- Oncothyreon (ONTY, Chart, Download SEC Filings)
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